Antigenic Variants of Influenza B Virus
نویسندگان
چکیده
منابع مشابه
Antigenic Variants of Influenza A2 Virus.
From 1967 to 1971 little antigenic variation was detected in the prevalent influenza B viruses but in December 1972 a new antigenic variant of influenza B was isolated in Hong Kong from sporadic cases of influenza. The new variant, B/Hong Kong/5/72, possessed a haemagglutinin antigen which showed considerable antigenic differences from that of former influenza B strains while its neuraminidase ...
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Influenza B virus Yamagata group strains, isolated in the 2000 to 2001 influenza epidemic season, reacted poorly to the polyclonal ferret sera prepared against strains isolated earlier. The results of genetic analysis clarified that a point mutation of the nucleotide at position 126 in the HA1 region and the corresponding one-amino-acid substitution altered viral antigenicity.
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In an attempt to simulate conditions in the human population between epidemics of influenza, the influenza A virus (PR8 strain) has been serially passed in mice partially immunized with this virus. The antigenic variant which emerged in the course of these passages has been described (1). This variant was capable of multiplying in the lungs of vaccinated mice which were fully resistant to chall...
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ژورنال
عنوان ژورنال: BMJ
سال: 1973
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.4.5885.127